Insulin Resistance and Insulin Therapy

Insulin resistance? What is it? Well, it is defined as the body's inability to use the insulin it manufactures. This may be associated with high blood pressure, obesity and elevated levels of fat in the blood. This is where insulin therapy may come in.

The estimate of the number of people with insulin resistance is forty million in the US. When unchecked, it leads to diabetes. Type 1 needs insulin but Type 2 can still be treated with lifestyle changes and medication, but may need insulin therapy.

Insulin resistance or not, it is good to understand how insulin therapy works. Before the advent of diabetes, the body makes enough insulin to deal with each rise of the blood sugar. It makes more when you eat and less between meals and at night.

The injected insulin does not work this way. It takes some time for it to begin working so it is given before meals. The injection works very hard when it reaches its peak after which it begins to decrease. That said, wouldn't you rather have insulin resistance or pre diabetes?

Reading up on insulin resistance has shown us that the doses will be scheduled in such a way that the short-acting one will peak by the time you eat. Then the longer-acting one will aid in holding the blood sugar down between meals and at night. You see, the flexible delivery system has made it possible to match the doses to one's lifestyle.

As we read the facts on insulin resistance, we learned there are different kinds of insulin and each functions differently. The treatment is easy to follow because with changes in one's routine, it is necessary to adjust the timing and dose to accommodate the different activities and schedules. You have to work with the health care team to learn how to make the adjustment. Here are the kinds:

  • Regular Insulin (short acting)
  • NPH (or Lente, longer acting
  • Ultra Lente (Very long acting)

They are available in pre-mixed type. This will free you from having to mix them yourself. I know that you can learn to mix the different types of insulin in the same syringe yourself. To do this, lightly roll the bottle back and forth before drawing it up into the syringe. It is good to know this just in case you will need to do it later but the pre-mixed form can serve the same purpose.

Our readings on insulin resistance led us to some tips about this type of treatment. Here they are:

  • When buying your supply, make sure with the pharmacist that the insulin is the right one for you.
  • Check the expiration date. Make sure it does not expire before you finish using it because the expiration can make the supply lose its strength.
  • Short-acting insulin looks as clear as water while the other kinds appear cloudy or milky after mixing.
  • While unopened, store the insulin in the refrigerator while opened ones can be kept at room temperature for as long as thirty days.
  • Insulin should never get frozen or get more hot than the room temperature.

Here are some helpful tips regarding the dose:

  • Insulin is calculated in units.
  • There are 1000 units in each bottle.
  • The syringe is also marked in the same units but make sure it holds enough units for your dose.
  • A more simple way may be is to use an insulin pen where you dial up the number of units you need and press the button to deliver it.

The best place to inject the insulin?

  • The upper arm's outer area
  • A little above the waist
  • The buttock's upper outer area
  • Just behind the hip bone
  • The front of the thigh between the knee and the top of the thigh
  • The abdomen except the navel area

The place where to injected can be rotated. The insulin stings less when it is at room temperature. Remember not to rub the area where it is injected. Applying a little pressure will do the trick. After all this, you can tell we learned a lot from reading the facts on insulin resistance.

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There is news from an Israeli-based company that they have developed and patented an oral insulin capsule. This is news that's easier to swallow by the diabetics who need insulin to survive but hate the needles.

This oral insulin capsule that was created by Oramed copies the way the body deals with this hormone in the way it is produced, regulated and distributed. The capsule makes the insulin enter the liver from the gastrointestinal track. The liver then regulates the hormone intake before passing it to the circulatory system.

As of January 18, 2008, Oramed (the company that developed this oral insulin capsule) recently completed its Phase 1A clinical trials. The trials were successfully evaluated as to the safety and tolerability of the product.

End of Newsalert!

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