Diabetes Medical News
The diabetes medical news that may help you with the management of your condition are here. Diabetes is not an easy condition to manage and it is a life-long process. It requires a commitment on our part in order to beat this.
These diabetes medical news are not the latest but they do give us an indication of the work that is on-going. And one way we can make sure that we are on the right track is keeping abreast of the diabetes medical news.
More News Related to Diabetes
Sirtuin Protein Identified That May Help Fight Obesity and Diabetes
August 18, 2007
A study led by the Joslin Diabetes Center found a protein in fat cells. This may help learn how fat is produced and stored and so may lead to new treatment to lower the risk for developing Type 2 diabetes. This newest research can be seen in the August 2007 issue of Cell Metabolism.
Stronger Heart Failure Warning
August 17, 2007
Labels on pioglitazone or rosiglitazone have given warning since 2002 about the possible effects of these drugs to cause retention of fluid that could lead to heart failure. These labels have also recommended for the health care team to watch for signs of heart failure among the patients who use these drugs. FDA official Steven Galson announced that they carefully monitor data for drugs and that they take the necessary action to let the health care team and the patients know of any relevant info. The trouble is that despite the warnings, these are still being prescribed.
FDA further said that some who use thiazolidinedione gain considerable weight and edema and some continued to use it and died. The warning labels inform the health care team to watch for signs of heart failure at the start of this therapy and whenever the dosage is increased. They added that if any symptoms appear, dosage should either be reduced or discontinued.
Takeda Pharmaceuticals America Inc.market products that contain Pioglitazone under the brand names Actos, Actoplus Met, and Duetact while Glaxo SmithKline market products that contain Rosiglitazone with these brand names: Avandia, Avandamet, and Avandaryl. This is one diabetes medical news we need to help fight this condition.
Diabetes Drugs Get Black-Box Warning
August 14, 2004
FDA announced today that it will oblige some diabetes drugs to carry its black-box warning that they are associated with increase in heart failure. These drugs include both Avandia and Actos but what the FDA failed to mention was the concern regarding GlaxoSmithKline's Avandia that it could boost the risk of heart attack. Both Avandia and Actos have been exposed as having increased the risk of heart failure which is different from heart attack. It is described as the heart being unable to pump blood correctly. The Food and Drug Administration recommended last June to make the warning stronger by adding a black box to labels of these drugs. Last month the FDA had a meeting with a panel of medical experts to discuss this issue. This is because last May Dr. Nissen of Cleveland Clinic published his analysis of Avandia implicating it with increased heart attack. The panel concurred and recommended adding a black-box warning to the drugs' labels. FDA has not acted on this recommendation. ***ReutersPublished: Monday, August 13, 2007Article tools
The mayor of Milan announced today that overweight residents of an Italian town will be paid to lose weight. Mayor Gianluca Buonanno said that men living in the northwestern Italian town of Varallo will receive 50 euros ($70) for losing 4 kg in a month while the women will receive the same amount if they lose 3 kg. In addition, the mayor said that the people who can keep the weight off for 5 months will get another 200 euros.
People are accepting the challenge because they said they really need to lose weight but that it was easier said than done so the mayor suggested that they go on a group diet. The town of 7,500 people started the campaign on Friday and some residents have already signed up.
This is great because it has been reported that around 35 per cent of Italians are overweight or obese because the country's healthy Mediterranean diet has been replaced by the processed foods rich in fat, sugar and salt.
May 21, 2007
Study Says Diabetes Drug Boosts Heart Attack
A new study found that one of the biggest sellers of medication for Type 2 Diabetes considerably raises the risk of heart attack and death. Patients taking the drug rosiglitazone should be on the alert due to this report in the New England Journal of Medicine.
This drug is usually sold under the brand names Avandamet and Avandia. According to the researchers the risk of cardiovascular death has soared by 64 per cent while the risk for heart attack has gone up by 43 per cent. These are significant increases to say the least.
Steven Nissen, the lead writer of the study who is also the chairman of cardiology at the Cleveland Clinic said the results of the study have raised serious concerns about the medicine’s safety in relation to cardiovascular problems for people who are already at risk because of diabetes.
Heart disease is one of the most serious complications of diabetes. With the medicine that is supposed to help lower the risk, appearing to boost rather than lessen the risk of heart disease, it is no wonder the U.S. Food and Drug Administration issued an alert immediately.
The director of Food and Drug Administration for Drug Evaluation and Research, Steven Galson, also cautioned that changing the patients’ medication from rosiglitazone to their counterpart pioglitazone, sold under the brand names Actos and Takeda may pose an inherent risk as these drugs may also have an unfavorable effects on the heart.
The thing to do in this case is not to stop your medication until you have received medical advice. So don’t abandon this medication until you have talked to your doctor. Unfortunately, Health Canada has not returned calls so it is unclear the best action to take.
However, Health Canada which monitors drug safety in this country, has cautioned that both the Avandia and Avandamet have been linked to an uncommon vision problem called Macular edema. What is this, you asked? Well, it is the enlargement of the retina because of the fluid in the eye.
Millions of people suffer from diabetes, in particular Type 2 diabetes. This is a troublesome disease that harms the circulatory system. It is also known to be the most important cause of heart disease, blindness, kidney failure and amputation, if left untreated, that is.
The worldwide sales of Avandia from last year is said to have exceeded the U.S. $3 billion mark. That is probably why despite the original plan to publish the results of this study next month, June, 2007, it was released earlier due to clinical importance of the news.
What are the details of the research? The research team compiled and analyzed the results of 42 clinical trials. This involved 15,560 patients taking Avandia and 12,283 patients not taking the drug. The risk for heart attack and death from Avandia users were considerably higher.
This seems to bring our attention to the flaw in the drug approval system. Although, the drugs that show a continued decrease in blood glucose levels are approved for sale, it looks like the present standard used to approve drugs for diabetics is low. That is why the head of the study, Dr. Nissen said that drugs should be approved not only from the improvement of the blood sugar level but also if they show reduction of complications.
Watch this section for alerts; they will appear as they become available.
May 26. 2007
After his wife died from diabetes, Lee Iaccoca became a dynamic supporter of research to find a cure for the disease. He is known to have already donated over 20 million dollars to fund diabetes research and now he is leading the raising of money by going to the people. Here is the website if you want to join Lee: http//www.joinleenow.org
Dr. Denise Faustman of Harvard has reversed the diabetes in mice and would like to start the human trials with the help of Lee Iaccoca. The trouble is the patent for the drugs she needs has expired and so there’s not enough profitability from the research.
Brian Williams, the news anchor of NBC interviewed him last May 25, 2007 and Lee said he will now devote his time to raise money for diabetes research. We are just thankful for all these diabetes medical news that help us keep abreast on the ways and means of dealing with this condition.
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